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neoformans can disseminate to the central nervous system (CNS) by employing a Trojan horse mechanism, whereby it survives within macrophages in the bloodstream to cross the bloodbrain barrier

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10.1038/s41586-019-1678-1 174 ZhangH.JiaR.WangC.HuT.WangF

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A loss of function mutation in the GRK1 gene leads to stationary night blindness Oguchi type-2 where a severe retardation of dark adaptation of rhodopsin (the GPCR) in rod photoreceptors impairs vision at low light levels