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[DOI] [PubMed] [Google Scholar] 26.M, Ingersoll RT, Lykkesfeldt J, et al

The D759G mutation uncouples zinc sensitivity from Neto modulation We noted that standard extracellular solutions often contain trace amounts of contaminating zinc (nanomolar range), which can tonically inhibit other glutamate receptors such as NMDARs

This modification enhances resistance to hyaluronidase degradation, effectively extending the residence time at the injection site

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