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The inhibition of ATG5, a mediator of autophagy in hypoxic cancer, can induce cisplatin sensitivity in previously resistant cells (188), supporting the contribution of hypoxia-induced autophagy to the development of anticancer drug resistance

This novel strategy combining manipulation of enzymatic crosslinkers using exogenous LOXL2 supplementation appears to be a promising technique for engineering more physiologically relevant cartilage constructs (Kwon et al ., 2019)

However, a single method is not suitable for all and there is no shortcut approach to determine antioxidant activity

10.1016/j.prp.2022.153951 111 SarfsteinR.FriedmanY.Attias-GevaZ.FishmanA.BruchimI.WernerH

Genetic inactivation of the phospholipase A2 activity of peroxiredoxin 6 in mice protects against LPS-induced acute lung injury