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Description
According to the glutamate hypothesis, dysfunction of NMDA receptormediated neurotransmission has been implicated in the pathophysiology of negative symptoms in schizophrenia (Hu et al
Acta Vet Scand, 2008

Therapeutic VNS harnesses these same cholinergic pathways to modulate gastrointestinal function

Anandatheerthavarada HK, Biswas G, Robin MA, Avadhani NG

The preclinical data is solid

Robust dimensions of anxiety sensitivity: development and initial validation of the Anxiety Sensitivity Index-3
