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The fold-change values are from area-normalized peak intensities and represent percent changes in the DR group with respect to the control values, with negative values for decreases and positive for increases

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519 Ultimately, GLP-1RA, by regulating BMP4 and its effects on cell proliferation and metastasis, provides a promising treatment approach

Whereas changes in BMD occur over long periods of time, blood levels of bone turnover markers provide immediate information about bone activity and can be used to assess osteoporosis progression and monitor treatment