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10.1002/mnfr.200400049 282 SchrderP.AbeleC.GohrP.Stuhlfauth-RoischU.GrosseW

The first nootropic to use the term was a drug developed in the 1960s called piracetam.60 61 It was intended to treat anxiety and provide patients with a soothing experience that might even lull them to sleep.2 The effect was quite different than what its creators intended, as users reported sharper focus, and later testing pointed toward improved memory

[Google Scholar] Li, C

doi: 10.1016/j.tibs.2013.07.003

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In 3 uncontrolled trials, CoQ10 in doses of 100 to 600 mg per day was beneficial for migraine prophylaxis in adults