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doi: 10.1016/s0003-9861(03)00199-1

Historically, collagenase as a TOPICAL is a cream that can be applied to severe burns or skin ulcers to help remove dead skin tissue

Collectively, these findings raise the possibility that the mechanism of glucocorticoids increasing serum IGF-I levels is by directly inducing post-IGF-IR signaling resistance

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Overall, across the two repeat experiments for Cagri and CagriBB bound to the CTR, the conformational equilibrium between the bypass vs CT-like state was similar, suggesting that the salt bridge/ionic lock is sufficient to preferentially stabilize the bypass conformation at CTR (Supplementary Fig

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