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It positively correlates with plasma levels of bile acids and hepatic mRNA expression of cholesterol 7 alpha-hydroxylase (CYP7A1) in mice, which trigger hepatic lipogenesis and hepatic steatosis via the bile acid-mediated hepatic farnesoid X receptor (FXR) signaling pathway [113]
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& Orentreich, N
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Thiam A, Farese R Jr, Walther T
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