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Among patients with UC, genetically determined increased levels of MD-2 ( LY96 ) (rs11465996) and CD14 (rs2569190) 15, 17, 18 were associated with nonresponse, indicating that a high activity of TLR4 was associated with nonresponse among patients with UC

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Tang YQ, Yuan J, Miller CJ, Selsted ME: Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of -defensins from rhesus macaque leukocytes

vinca alkaloids and taxanes), tyrosine kinase inhibitors (but not erlotinib, gefitinib and sorafenib), and immune-modulating agents, including glucocorticoids and mammalian target of rapamycin inhibitors (but not everolimus)