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Metformin is a well-established diabetes medication with a generally strong safety profile when prescribed appropriately
It is defined by vitamin B 12 deficiency in the presence of sufficient dietary vitamin B 12 intake, negative Schilling test, and lack of anti-intrinsic factor antibodies.30 Clinically, it is diagnosed by exclusion of other disorders or factors causing vitamin B 12 deficiency
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Dietary deficiency: Strict vegans or very poor diets may lack animal-source B12
