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Impinging on the same neuronal targets, ghrelin exerts opposite effects and is thus an anabolic hormone

When the peptide activates or modulates these receptors, it triggers intracellular signaling involving cAMP elevation, protein kinase A activation, and hormone-sensitive lipase stimulation, ultimately leading to triglyceride breakdown and fat mobilization

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doi: 10.1007/s12035-015-9364-2

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