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C., and EstradaBellmann I., Microalbuminuria as a Potential Biomarker for Parkinson's Disease Severity: A Hypothesis, Medical Hypotheses 149 (2021): 110510

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The activation of GRB2 results in signal transduction via the activation of the guanine nucleotide exchange factor, SOS (son of sevenless encoded by the SOS1 gene) which in turn activates the monomeric G-protein, RAS

The results show that when the cellular suspension was fed with AsA, the intracellular level of AsA increased, but the incorporation of radioactive D-[U- 14 C]-mannose into AsA decreased, so the feedback inhibition of AsA biosynthesis by AsA was clearly observed in vivo (Wolucka and Van Montagu, 2003)

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