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Freezing reconstituted multi-use vials is generally not recommended because freeze-thaw cycles can damage peptide structure and affect solution chemistry

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Lets walk through some of the most common myths surrounding AOD 9604 and look at what the available information actually tells us

It forms fatty acids and glucose

protein misfolding, mislocalization of TDP-43 to the cytoplasm, ER stress, inhibition of ER-Golgi transport, and apoptosis, in neuronal cells expressing pathological forms of TDP-43 or SOD1 (Parakh et al., 2020)
