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(1999) published that aberrant hypermethylation of the TSG p16, the putative metastasis suppressor gene death-associated protein kinase (DAPK), GSTP1, and the DNA repair gene O6-methylguanine-DNA-methyltransferase (MGMT) is observed in non-small cell lung cancer (NSCLC) tumors but not in any paired normal lung tissue

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The mitochondrion is a major intracellular source of ROS, producing superoxide and hydrogen peroxide as metabolic byproducts [102]

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However, as Witemburg did not use adjustment for optimal editing in the MEGA-PRESS sequence [93], the performance of MEGA-PRESS may have been underestimated in this study