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Mitochondrial function was severely compromised on multiple levels, including abnormalities in mitochondrial biogenesis (PGC1), nutrient sensors regulating fatty-acid entry into mitochondria (pAMPK/AMPK, SirT3, CPT1b), mitochondrial -oxidation of fatty-acids (HADHA, PPAR), electron transport chain complexes (I, II, III, V), ATP synthesis (ATP5A), and mitophagy (PINK1)

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The potential effects of Centella asiatica ethanolic extracts as an anti-inflammatory agent through decreasing TNF- expression in indomethacin-induced gastric ulcer model rats

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Soria Lopez et al., 2019)

Control of cytochrome c oxidase activity by nitric oxide