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IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3beta-Nrf2-BNIP3 Pathway
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doi: 10.1016/J.BBRC.2009.02.130 127 KightKEMcCarthyMMMcCarthyMM

10.1016/j.cell.2011.02.010 Cell 119 SinghB
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And like any living system, it produces wasteunstable molecules called free radicals
