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Thioredoxin glutathione reductase (TGR) is essential for schistosome survival and a validated drug target

Therefore, rigorous safety evaluations are essential to address the potential adverse effects and toxicity of plant products, which is crucial for patient safety

In summary, the highly interconnected nature of redox homeostasis and glycolysis in cancer cells provides an opportunity for synthetic lethal drug combinations targeting GSH synthesis and glucose metabolism

385 Another novel proteasome inhibitor, CEP-18770, demonstrates superior and more sustained dose-dependent suppression of tumor proteasome activity than Bortezomib in medulloblastoma

Proc Natl Acad Sci U S A 102, 52565261

reported 67 human cases of H5N1, of which 40 were linked to exposure to diseased cattle (PAHO/WHO, 2025)