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Postmortem analyses reveal excessive iron accumulation in the SNpc, correlating with dopaminergic neuron loss ( Studies show that -synuclein may bind iron directly, promoting its aggregation, while lipid peroxidation products further stabilize toxic oligomers ( 2.4 Neuroinflammation and cytokine activation Chronic neuroinflammation is another driver of PD progression

While they are both vital for wellness, they work in different "departments" of your internal biology