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Recent experiments showed a surge in IL-6, IL-1, and TNF- levels within irradiated mice serum, which is revoked in MyD88-deficient animals

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The role of TWEAK/Fn14 in the pathogenesis of inflammation and systemic autoimmunity

However, as the definitive treatment to deliver complete relief from NP for long periods remains lacking, many researchers are working on addressing the underlying complex mechanisms to target CNP in SCI patients