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Extracellular matrix (ECM) adhesion and remodeling are critical for the cell migration of tissues [80]

Mechanistically, we find that GSH promotes lipid abundance by repressing NRF2, a transcription factor induced by oxidative stress

Autoimmune diseases are becoming increasingly prevalent, and their corresponding treatments can result in further immunosuppression, which can lead to systemic infections that potentially cause death [75]
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In addition, the dual InsR/IGF-IR inhibitor linsitinib can prevent the emergence of breast cancer cells that are resistant to long-term estrogen deprivation or antiestrogen treatment and inhibit growth of established ER+ breast cancer xenografts in ovariectomized mice [107]

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