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[3] Signs, symptoms and complications [edit] Vitamin B 12 deficiency appears slowly and worsens over time, and can often be confused with other conditions

Suggested starting points to discuss with your clinician Deficiency without malabsorption: 1,0002,000 mcg oral cyanocobalamin daily until normalized, then weekly or monthly maintenance per labs (AAFP)

Your Nurse Practitioner will recommend a schedule that makes sense for your specific situation

Some practitioners use this as a taper during weeks 9 to 12 of longer protocols, easing the body out of daily frequency before a full rest period

B12 deficiency can also cause water retention, constipation, muscle weakness, fatigue, and weight loss

It also depends on how well the person responds to treatment and their overall health