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However, individuals with Wilson's disease, a condition affecting copper metabolism, should avoid GHK-Cu entirely

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Subsequently, 1 ml of a 2-M Na2SO4-55 mM TBA solution was added, followed by incubation in a 95C water bath for 45 min, and an additional incubation in ice for 5 min

Glorioso C, Sabatini M, Unger T, Hashimoto T, Monteggia LM, Lewis DA et al (2006)

sublingual/injection routes can bypass this
