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A: This must be discussed with your doctor
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Weight loss ranged from 9.3% to 17.4% of baseline body weight depending on the dose and population studied

Educate patients and their families about the symptoms of lactic acidosis and if these symptoms occur, instruct them to discontinue XIGDUO XR and report these symptoms to their healthcare provider

Intestinal release of GLP-1 augments initial insulin secretion in vivo in part through a vagal-vagal reflex leading to cholinergic stimulation of islet beta cells

GLP-1RAs and SGLT2is also provide sustained weight loss via different mechanisms
