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Description
it is a critical component of hemoproteins found in all tissues
Dietary B12 found in food is bound to binding proteins, from which it is released in the stomach by pepsin and the acidity of secreted hydrochloric acid

Cell 2012, 148 (12), 2428

2005;118(Pt 1):718

Probiotics, Prebiotics, Synbiotics, and Postbiotics: Human Microbiome and Human Health

The GLP-1 and GIP/GLP-1 receptor agonists present one of the possibilities in this regard