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Meanwhile, seroconversion of anti-double-stranded DNA antibodies appear in these patients (anti-dsDNA decreased from 157 IU/L to 12 IU/L (P = 0.03)).These findings suggest that daratumumab could offer new possibilities for managing resistant lupus nephritis LN ( Lennard Ostendorf and colleagues administered daratumumab to address severe and life-threatening cases of systemic lupus erythematosus (SLE) in two patients

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The tinnitus may be significant enough to interfere with an individual's activities of daily living

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