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Adaptive plasticity of IL-10+ and IL-35+ Treg cells cooperatively promotes tumor T cell exhaustion

Redox-responsive nanoparticles, triggered by glutathione, release drugs in ROS-rich environments, as shown by indomethacin-loaded polyprodrug amphiphiles reducing inflammation (6)

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Next, we measured the cristae width of hundreds of mitochondria and determined that rapamycin-treated CAR T cell products had significantly looser mitochondrial cristae, which is consistent with their less-activated metabolic state (Fig

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Ribero et al., 2017)