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It is found in most tissues but shows up in higher concentrations in the liver

(224) demonstrated that Curene had significantly better oral bioavailability (95%) than CP-01 and regular curcuminoids and was safe for use under trial conditions

Department of the Interior, Fish and Wildlife Service, Laurel, MD EPA (1986) Air quality criteria for lead

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Humane endpoints: Animals were euthanized if tumor volume exceeded 2000 mm, if tumors reached 10% of body weight, if body weight loss exceeded 2025%, or if signs of cachexia or severe distress were observed