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Mice were initially group housed (three/cage) and allowed to acclimate to the colony environment maintained at a constant temperature (2123C) and humidity (4050%) on a 12-hour light-dark cycle (lights on 06001800 h)

2 Studies have shown that, in cancer-associated fibroblasts (CAFs), treatment with 5-Amino-1MQ not only modifies histone methylation patterns but also suppresses tumor-supportive metabolic functions

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World Health Organization, Geneva, p 2016 Suvi K et al (2017) IDF diabetes atlas, 8th edn 2017
