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doi: 10.3390/ijms24043735

MiR-107 regulates the expression of the putative pituitary tumor suppressor gene Aryl hydrocarbon receptor-Interacting Protein (AIP) ( MiR-26b and miR-128 were found to be respectively upregulated and downregulated in GH-producing pituitary tumors ( MiR-23b and miR-130b were reported to be downregulated and to inhibit cell growth in pituitary adenomas ( Somatostatin receptor subtype 2 (SSTR2) was found to be increased in adenomas with respect to normal pituitaries while it was decreased in patients non-responding to treatment with long-acting Somatostatin analogues (SSAs) with respect to responders ( MiR-338-3p inhibition reduced both GH mRNA and protein levels in GH3 cells and reduced cell proliferation ( A recent study reported different miRNA signatures among non-functioning pituitary adenomas, prolactin-secreting pituitary adenomas and GH-secreting pituitary adenomas compared with normal pituitary glands

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