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3-PUFAs are important constituents of membrane phospholipids and exert an important effect on modulating the physicochemical properties of membranes, which in turn affects cellular functions

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In addition, these products can hinder DNA and RNA from replicating, as a result of acting as physical obstacles to DNA polymerase and RNA polymerase and facilitating replication fork stagnation formation, leading to chain breakage that can consequently lead to chromosomal abnormalities[37] [38]