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In recent decades, the following treatments for IC/BPS have been recommended as replenishment of the glycosaminoglycan layer to control urothelial defects, administration of amitriptyline or imipramine to inhibit neurological hyperactivity, suppression of allergies by antihistamines, and non-steroid anti-inflammatory drugs for pain control (Homma et al., 2020)

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[DOI] [PubMed] [Google Scholar] 109.Taylor CT & Colgan SP Regulation of immunity and inflammation by hypoxia in immunological niches

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