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Unexplained fatigue despite adequate rest, decreased training capacity without apparent cause, or slow recovery between sessions all warrant investigating your B12 status

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Translational durability and long-term safety remain unresolved

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Not dramatically smaller, but the stubborn lower belly pouch I had been carrying around for a decade was starting to soften

However, if extremely high doses are given for a long time, pyridoxine can cause nerve damage leading to numbness or tingling in the hands and feet (peripheral neuropathy)