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It converts lipid hydroperoxides into less harmful lipid alcohols, preventing oxidative damage (91,92)

Subsequently, the expression levels of Nrf2, HO-1 and ferroptosis-related markers in the renal tissues of mice from the DN and DAPA groups were evaluated

They are fundamental biological processes that operate across all vascularized tissue types

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According to the latest research, the excess of FAO results in inadequate mitochondrial function, which can lead to impairment of the electron transport chain

In lupus-prone females, reduced abundance of Erysipelotrichaceae and Bifidobacterium, with increased Lachnospiraceae and Bacteroidetes S247 abundance, has also been reported ( These findings suggest that microbiological dysbioses specific to sex, more precisely the increased prevalence of Lachnospiraceae in females, may account for the earlier onset and greater severity of lupus symptoms