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They are also necessary for the interconversion of amino acids such as the metabolism of histidine to glutamic acid and the interconversion of serine and glycine

Typical symptoms associated with early-onset disease are feeding difficulties, failure to thrive, hypotonia, seizures, pigmentary retinopathy, developmental delay, and macrocytic anemia

Many patients begin to notice improvements in energy and body composition within a few weeks of starting therapy

Despite this, we have put together a list of the warning signs of excess B12 as it is important to be informed about the supplements you are taking and how to responsibly administer them at a safe dosage