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Nutritional influence on serum ammonia in young patients receiving sodium valproate

The PPI group provided structured feedback via an online survey

Dietary carnitine is taken up from the intestinal lumen into the enterocyte by an active transport mechanism, but it passes across the serosal membrane into the circulation by simple diffusion

As mentioned earlier, L-carnitine participates in the transport of long-chain acyl groups from the cytoplasm to the mitochondria, thus regulating the concentration of acyl-CoA and CoA in the cytosol and mitochondria and protecting correct cell metabolism [76,77]

CoQ10 transfers electrons from complex I and II to complex III, which is crucial step to create proton pump gradient across the membrane for generating ATP by complex V

Methods Settings and study population Subjects were identified retrospectively from medical records of 14 participating Italian sites (representative of the entire peninsula) according to the following inclusion criteria: aged 18+ years at ALS diagnosis, definite or probable or probable laboratory-supported ALS according to the revised El Escorial diagnostic criteria [12]