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A recent study has shown that the influenza virus matrix 1 protein can induce the production of proinflammatory cytokines and cellular ROS as well as trigger cell death through the activation of TLR4 signaling 28

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Compared to humans and mice, rats have a higher basal level of antioxidant defense gene expression, and rats have a greater capacity to respond to cellular stress, which makes them generally more resistant to drug toxicity [127]

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[23] Increased longitudinal cohort studies or randomised controlled trials are required to understand the mechanisms between vitamin B 12 and metabolic outcomes, and to potentially offer interventions to improve maternal and offspring health