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IL-1 has been shown to directly induce catabolism in C2C12 derived myotubes, suggesting a direct causal relationship in cachexia [23]

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There were no significant differences between the ipamorelin and placebo groups in the key and secondary efficacy analyses. Myth 2: These Peptides Accelerate Tumor Growth Both CJC-1295 and Ipamorelin indirectly increase GH and IGF-1 levels, and while some tumors have IGF receptors, the link between IGF-1 and cancer still remains unclear

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2017 Jul;67(7):1127

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