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The predominant sham procedure was a non-penetrating needle procedure using a blunt and retractable needle and guide tube or placement on non-traditional acupuncture points [39, 40], and better efficacy of true acupuncture compared to sham acupuncture was found

[DOI] [PMC free article] [PubMed] [Google Scholar] Moriggi M., Cassano P., Vasso M., Capitanio D., Fania C., Musicco C., Pesce V., Gadaleta M.N., Gelfi C

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Abstract Background: Fatigue of unknown origin is a hallmark symptom in chronic fatigue syndrome (CFS) and is also found in 20% of hypothyroidism patients despite appropriate levothyroxine treatment