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Description
IGF-1/-2-neutralizing monoclonal antibodies inhibit various IGF signaling pathways at the same time but have a lower risk of hyperglycemia than IGF-1R/INSR tyrosine kinase inhibitors, as they do not affect insulin receptor-, which regulates glucose homeostasis [116]

Formononetin ameliorates dextran sulfate sodium-induced colitis via enhancing antioxidant capacity, promoting tight junction protein expression and reshaping M1/M2 macrophage polarization balance

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Thus, the definitional and diagnostic challenges of IMI demand a paradigm shift

The "expected pattern" for this signaling pathway if the pathway were activated

Routes of administration studied: Oral route: Thanks to its stability in acidic environments, BPC-157 can be administered orally
