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[17] Dehydrationwhich may occur due to reduced fluid intake or gastrointestinal side effectscan also exacerbate musculoskeletal symptoms

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None of this requires perfection

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Prescription weight-management medications may be used (in combination with a reduced-calorie diet and increased physical activity) for people with one of the following conditions: A body mass index (BMI) of 30 or higher A BMI of 27 or higher with a weight-related condition, such as high blood pressure or type 2 diabetes GLP-1s and weight-management medications may also be prescribed for reasons outside of this list