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Description
Glutathione - "The Master Anti-Oxidant", helps promote cellular growth and repair, DNA synthesis and repair and slows the ageing process

The shift in their TH-1 or TH-2 systems remains constant and does not change over the course of the autoimmunity

FIGURE 2 The accumulation of methylmalonic acid (MMA) and Hcy because of these disruptions leads to oxidative damage and impaired methylation

The second hit model suggests that in TTP, besides ADAMTS-13 deficiency, endogenous (antibodies or cytokines) and/or exogenous (virus or drugs) factors induce endothelial activation leading to an uncontrolled WPBs degranulation and, finally, to endothelial dysfunction (144)

10.1007/s11356-017-0579-9 4 AliM

NO is efficiently converted into low-molecular-weight SNOs (e.g., S-nitrosoglutathione [GSNOs]), which convey the large part of NO bioactivity
