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The very limited IL-1 formation as reported in mice123,124 was also confirmed in APAP overdose patients111, suggesting that inflammasome activation and IL-1 formation are of limited importance for APAP-induced liver injury in mice and humans

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[DOI] [PubMed] [Google Scholar] Anderson CP, Tsai J, et al

Activating these receptors modulates mood, movement, appetite, pain and sensation, memory, and perception