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Unlike benzodiazepines or other sedatives, it doesn't appear to create tolerance requiring escalating doses or produce withdrawal symptoms upon cessation

doi: 10.1136/bmj.m2031 [DOI] [PMC free article] [PubMed] [Google Scholar] [31].Lee DH, Rezende LFM, Joh H-K, et al

Platelet aggregation Platelet aggregation is one of the first steps in the formation of blood clots that can occlude coronary or cerebral arteries, leading to myocardial infarction or ischemic stroke, respectively

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Epub 2017 Mar 1

Bose P, Masarova L, Pemmaraju N, Bledsoe S, Daver N, Jabbour E, Kadia T, Estrov Z, Kornblau S, Andreeff M, Cortes J, Jain N, Borthakur G , Alvarado Y, Huynh-Lu J, Nguyen-Cao M, Richie M, Dobbins M, McCrackin S, Zhou L, Pierce S, Wang X, Pike A, Garcia-Manero G, Kantarjian H, Verstovsek S