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Trial outcomes were measured in weeks and months , not days

5-Amino-1MQ Also known as: 5-amino-1-methylquinolinium, NNMTi TL;DR Increases intracellular NAD+ levels via NNMT inhibition (preclinical) Reduces body weight and white adipose mass in diet-induced obese mice Improves grip strength by up to 60% in aged mice when combined with exercise Suppresses lipogenesis in adipocytes without affecting food intake Community-Reported Side EffectsAnecdotal

NNMT is overexpressed in adipose tissue of obese subjects, and its inhibition has been explored as a strategy to modulate methyl group flux and NAD+ precursor availability
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These hormones also contribute to improved recovery, energy, and metabolism

[DOI] [PubMed] [Google Scholar] Higgins 2002 Higgins JP, Thompson SG
