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Permeabilization was performed using 0.5% Triton X-100 (Sigma) for 5 min at room temperature

Studies show it has a longer half-life and higher bioavailability, but poor aqueous solubility (Zang et al., 2014

Side effects are minimal, weight loss continues at a steady rate, and body composition improvements accelerate as the cumulative effects of both compounds manifest

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In contrast, inducing autophagy with rapamycin (100 nM) attenuated SIPS
