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Accordingly, the chronic use of these substances, of which fentanyl is the most frequently consumed, represents an additional risk of liver damage in patients with underlying chronic liver disease

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The peptide demonstrates a capacity to counteract organ damage caused by toxic agents (alcohol, NSAIDs, and chemotherapy compounds) in animal studies

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BMJ (Clinical research ed.) 380:24 Tang S, Zhang C, Oo WM, Fu K, Risberg MA, Bierma-Zeinstra SM, Neogi T, Atukorala I, Malfait AM, Ding C, Hunter DJ, Osteoarthritis (2025) Nat Reviews Disease Primers 11(1):10 Li H, Yuan Y, Zhang L, Xu C, Xu H, Chen Z (2024) Reprogramming macrophage polarization, depleting ROS by astaxanthin and thioketal-containing polymers delivering rapamycin for osteoarthritis treatment

Large numbers of mast cells are found in the skin, bronchial tree mucosa, and intestinal mucosa