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In one study, a cohort of 99 patients with Wilson disease was compared to 32 healthy controls

Mood Enhancement: Some studies suggest that B-12 injections may play a role in mood regulation and emotional well-being, potentially alleviating symptoms of depression and anxiety

Well-designed placebo RCTs with vitamin B12 monotherapy are not available

The latter is considered less efficient and may bring about toxic metabolic byproduct formation

Proteins assembled in the ER are rich in disulfide bonds that help to promote efficient folding and oligomerization of nascent polypeptide chains [73]