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Furthermore, increasing Nrf2 levels are associated with a reduction in TNF, IL-6, Bax, and p38 levels, suppressed NFB activation, and upregulated Bcl-2 expression, demonstrating anti-inflammatory and anti-apoptotic effects in STZ-induced DKD rats [431]
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By conceptualizing tobacco-based bioenergy farming as an integrated agro-ecosystem, it is feasible to sustain or even enhance ecosystem services while generating feedstock for biofuels

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The effect of sperm DNA fragmentation on male fertility and strategies for improvement: A narrative review
