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Hormetic concentrations of hydrogen peroxide but not ethanol induce cross-adaptation to different stresses in budding yeast
In this therapeutic ADC, the thioether linker contains cyclohexane and a maleimidomethyl group (maleimidomethyl cyclohexane-1-carboxylate, MCC linker) complexed with a thiol-containing maytansinoid payload (DM1)
The 10 patients enrolled in the prospective clinical trial (Table 1) provided informed consent under the trial IRB protocol 2017-0201 and IRB protocol PA11-1045
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doi: 10.1046/j.1365-2362.2000.00710.x
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