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Low et al 2007 [edit] "Molecular Evolution of Glutathione S -Transferases in the Genus Drosophila "

In turn, overlaying the naphthyl groups of NACPA and NEIH positions the 3-COOH group extending from the isoxazole ring of NEIH such that it aligns with the distal COOH group of l-Glu and delineates a second lipophilic pocket occupied by the 2,4-dinitrophenyl moiety (Figure 5D and E)

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Other studies have also shown that it exerts hepatoprotective effects through its anti-oxidant activity